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Intraneuronal amyloid oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo

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Some researchers have reported that PCIF1 diminishes ferroptosis in CD8 + T cells predominantly through the upregulation of genes that regulate ferroptosis, including FTH1 and SLC3A2 (208)

MMP plays an important role in the regulation of ECM remodeling and can degrade mostly various proteins in ECM, promoting tumor cell proliferation and EMT